Anti-Aging with Dr. Gary Jayne Rothfeld
629 Park Avenue, New York City
The Clinical Philosophy
Aging is neither sudden nor accidental. It is a progression governed by biology: the slow unraveling of collagen fibers, the diminishing elasticity of elastin, the steady depletion of hyaluronic acid, and the gradual weakening of mitochondrial energy. The skin barrier becomes fragile, vessels lose tone, and oxidative stress accumulates silently within tissues.
To treat aging is to understand its machinery. Each wrinkle, each shift in contour, is the outward expression of cellular decline. At 629 Park Avenue, I address these changes with a philosophy that is both clinical and humanistic. We restore where volume is lost, protect where barriers have thinned, and rekindle cellular vigor where exhaustion has set in.
I am in my seventies, though I am consistently mistaken for a man twenty to thirty years younger. This is not the result of luck or genetics but the deliberate orchestration of medicine, lifestyle, and discipline. My program rests on four pillars: advanced dermatologic treatments, structured exercise, precise nutrition, and a supplement regimen informed by evidence and always reviewed in the context of overall health.
Treatments that Restore Structure
Liquid Facelift
The face ages because volume declines, ligaments loosen, and skin thins. The liquid facelift corrects these changes by reintroducing structure with dermal fillers. Hyaluronic acid–based injectables replenish the cheeks, restore midface support, soften nasolabial folds, and refine the jawline. When combined with collagen-stimulating agents such as poly-L-lactic acid or calcium hydroxylapatite, the treatment not only corrects but triggers the skin to produce its own proteins anew. The effect is not a mask but a restoration, youth returned without distortion.
Non-Surgical Rhinoplasty
The nose anchors the face. Subtle changes in angle or projection can shift the entire balance of expression. Through carefully placed micro-injections of hyaluronic acid, dorsal humps can be softened, bridges refined, and tips elevated. This non-surgical approach achieves proportion in minutes, with minimal risk and no recovery period.
Comprehensive Skin Renewal
Skin reflects health at the cellular level. Lasers stimulate controlled injury, prompting fibroblasts to remodel collagen and elastin. Biostimulatory fillers extend this process, reinforcing dermal strength. Hydration therapies replenish hyaluronic acid, restoring suppleness. Over time, texture refines, pores diminish, and luminosity returns.
Nutrition and Exercise: The Foundation
Procedures may correct, but daily living sustains.
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Protein: Provides proline, glycine, and lysine for collagen synthesis.
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Polyphenols: Found in berries, green tea, and red wine, they reduce oxidative damage by stabilizing free radicals.
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Omega-3 fatty acids: Modulate inflammation, protect endothelial function, and reinforce lipid membranes.
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Hydration: Maintains cellular metabolism and dermal turgor.
Exercise is indispensable. I swim 2 miles each day, sustaining cardiovascular output and mitochondrial density. Resistance training prevents sarcopenia, supports bone density, and stimulates anabolic hormones such as growth hormone and IGF-1. Mobility and balance exercises preserve function, reducing risk of falls and injury.
Supplements in Practice
The supplement cabinet is a clinical arsenal. Each bottle has purpose, each dose a target. Yet supplementation must always be personal, tailored to an individual’s medical history, labs, and medications. Patients must review every regimen with their primary care physician.
Cellular Energy and Mitochondria
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Creatine: Recycles ATP in muscle and brain, supporting strength, endurance, and cognition. Studies suggest it may slow sarcopenia and aid neural resilience.
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Acetyl L-Carnitine: Transports fatty acids into mitochondria, enhancing energy production and offering neuroprotective benefits in aging nerves.
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Coenzyme Q10 (200 mg): A critical cofactor in mitochondrial electron transport. Supports cardiovascular health and functions as a lipid-soluble antioxidant.
Skin, Hair, Nails, and Connective Tissue
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Collagen peptides (powder and capsules): Hydrolyzed peptides stimulate fibroblasts, improve dermal thickness, and strengthen ligaments and tendons.
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Multi-collagen blends: Deliver type I, II, III, V, and X collagen for comprehensive connective tissue support.
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Vitamin C: Essential cofactor in collagen hydroxylation; neutralizes free radicals generated by UV light.
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Hyaluronic acid (oral): Maintains skin hydration, enhances viscoelasticity, and supports synovial fluid in joints.
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Ceramides and phytoceramides: Rebuild intercellular lipid layers of the epidermis, reducing transepidermal water loss.
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Biotin (10,000 mcg): Strengthens keratin proteins, improving hair density and nail resilience.
Circulation, Nerves, and Cognition
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Ginkgo biloba: Enhances cerebral perfusion, potentially improving memory and concentration.
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Vitamin B12: Prevents anemia, preserves nerve function, and is critical as absorption declines with age.
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Vitamin K2: Directs calcium deposition into bone while reducing vascular calcification.
Vision and Ocular Nutrition
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Ocuvite Adult 50+: Provides lutein and zeaxanthin to protect the macula, with antioxidants to defend retinal tissue against oxidative light injury.
Foundational Nutrition
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Omega-3 fish oil (EPA and DHA): Cardiovascular, neurological, and dermatologic support.
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Calcium with Vitamin D3: Maintains skeletal density and supports immune regulation.
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Multivitamin for men 50+: Fills micronutrient gaps in daily intake.
How I Organize the Day
Morning
Collagen peptides, vitamin C, biotin, hyaluronic acid, phytoceramides, multivitamin, B12, K2, calcium with D3, Ocuvite.
Midday or Pre-Workout
Creatine, acetyl L-carnitine, omega-3, CoQ10, ginkgo biloba. Training follows: swimming, resistance exercise, and balance work.
Evening
Multi-collagen complex, ceramides, and magnesium for recovery.
Safety and Clinical Oversight
Supplements are not benign. They interact with prescription medications, influence clotting, alter absorption, and affect hormone balance. Anticoagulants, thyroid hormones, and diabetes medications are common points of conflict. Every patient must bring their bottles to their physician and undergo medication reconciliation. What is beneficial for one may be hazardous for another.
A Living Example
To advocate a method without living it is hollow. I have lived it. My face and body are the testimony: a man in his eighth decade of life carried with the energy and appearance of mid-life. Decades of training, clinical knowledge, and structured habits converge in the mirror. The proof is not abstract. It is visible. It is repeatable. It is available to any patient willing to walk the same disciplined path.
Call to Action
For a program that unites science, artistry, and discipline, contact 212-644-4484 or request a consultation online. Bring your medications and supplements. Together we can design a regimen that is not only effective but safe, not only cosmetic but profoundly restorative.
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